I investigated your example and if the "second" note is different, there is no problem
However, I don't think one performer is able to play your first bar since an instrument is not able to "start" playing a note which is already produced by that same instrument. Your second bar seems to me an interpretation from a performer who is trying to play the "different" parts with only one instrument.
The only correct option for me is using different midi-channels since multiple instruments are necessary for what was put into one score.
Considering the technology for MIDI, I also fear that stripping off the note-off in a MIDI stream will be very hard to implement.
Special Note: Inserting a Multi-point Controller that contains control points that are scheduled at time offset well beyond the current beat can significantly add to the hesitation time between when you request play and actually hear the song start to play back.
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